Jennifer J. Wheler: search on Z-Library

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1

Safety and Antitumor Activity of the Multitargeted Pan-TRK, ROS1, and ALK Inhibitor Entrectinib: Combined Results from Two Phase I Trials (ALKA-372-001 and STARTRK-1)

Drilon, Alexander, Siena, Salvatore, Ou, Sai-Hong Ignatius, Patel, Manish, Ahn, Myung Ju, Lee, Jeeyun, Bauer, Todd M., Farago, Anna F., Wheler, Jennifer J., Liu, Stephen V., Doebele, Robert, Giannetta

Journal:

Cancer Discovery

Year:

2017

Language:

english

File:

PDF, 1.09 MB

english, 2017

2

Survival of patients in a Phase 1 clinic : The M. D. Anderson Cancer Center Experience

Jennifer Wheler, Apostolia M. Tsimberidou, David Hong, Aung Naing, Tiffiny Jackson, Suyu Liu, Lei Feng, Razelle Kurzrock

Journal:

Year:

2009

Language:

english

File:

PDF, 278 KB

english, 2009

3

A phase 1 study of hepatic arterial infusion of oxaliplatin in combination with systemic 5-fluorouracil, leucovorin, and bevacizumab in patients with advanced solid tumors metastatic to the liver

Apostolia M. Tsimberidou, Siqing Fu, Chaan Ng, Jo Ann Lim, Sijin Wen, David Hong, Jennifer Wheler, Agop Y. Bedikian, Cathy Eng, Michael Wallace, Luis H. Camacho, Razelle Kurzrock

Journal:

Year:

2010

Language:

english

File:

PDF, 254 KB

english, 2010

4

Phase 1 clinical trials in 83 patients with pancreatic cancer : The M. D. Anderson Cancer Center experience

Christos Vaklavas, Apostolia-Maria Tsimberidou, Sijin Wen, David Hong, Jennifer Wheler, Chaan S. Ng, Aung Naing, Cynthia Uehara, Robert A. Wolff, Razelle Kurzrock

Journal:

Year:

2011

Language:

english

File:

PDF, 269 KB

english, 2011

5

Prevalence of complementary medicine use in a phase 1 clinical trials program : The MD Anderson Cancer Center Experience

Aung Naing, Saneese K. Stephen, Moshe Frenkel, Chandtip Chandhasin, David S. Hong, Xiudong Lei, Gerald Falchook, Jennifer J. Wheler, Siqing Fu, Razelle Kurzrock

Journal:

Year:

2011

Language:

english

File:

PDF, 143 KB

english, 2011

6

Phase I clinical trial of hepatic arterial infusion of paclitaxel in patients with advanced cancer and dominant liver involvement

Apostolia M. Tsimberidou, Katherine Letourneau, Siqing Fu, David Hong, Aung Naing, Jennifer Wheler, Cynthia Uehara, Stephen E. McRae, Sijin Wen, Razelle Kurzrock

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 183 KB

english, 2011

7

A phase I trial of imexon, a pro-oxidant, in combination with docetaxel for the treatment of patients with advanced breast, non-small cell lung and prostate cancer

Stacy Moulder, Navneet Dhillon, Chaan Ng, David Hong, Jennifer Wheler, Aung Naing, Susan Tse, Amy La Paglia, Robert Dorr, Evan Hersh, Michelle Boytim, Razelle Kurzrock

Journal:

Investigational New Drugs

Year:

2010

Language:

english

File:

PDF, 118 KB

english, 2010

8

Safety, pharmacokinetics, and activity of EZN-2208, a novel conjugate of polyethylene glycol and SN38, in patients with advanced malignancies

Razelle Kurzrock, Sanjay Goel, Jennifer Wheler, David Hong, Siqing Fu, Keyvan Rezai, Sonia K. Morgan-Linnell, Saik Urien, Sridhar Mani, Imran Chaudhary, Mohammed H. Ghalib, Aby Buchbinder, François Lo

Journal:

Year:

2012

Language:

english

File:

PDF, 458 KB

english, 2012

9

Phase I clinical trials in 85 patients with gynecologic cancer: The M. D. Anderson Cancer Center experience

John Moroney, Jennifer Wheler, David Hong, Aung Naing, Gerald Falchook, Diane Bodurka, Robert Coleman, Karen Lu, Lianchun Xiao, Razelle Kurzrock

Journal:

Gynecologic Oncology

Year:

2010

Language:

english

File:

PDF, 446 KB

english, 2010

10

Adjuvant Therapy With Aromatase Inhibitors for Postmenopausal Women With Early Breast Cancer: Evidence and Ongoing Controversy

Jennifer Wheler, Melissa Johnson, Andrew Seidman

Journal:

Seminars in Oncology

Year:

2006

Language:

english

File:

PDF, 159 KB

english, 2006

11

Clinical Outcomes of Patients With Breast Cancer in a Phase I Clinic: The M. D. Anderson Cancer Center Experience

Jennifer Wheler, Apostolia M. Tsimberidou, Stacy Moulder, Massimo Cristofanilli, David Hong, Aung Naing, Raminder Pathak, Suyu Liu, Lei Feng, Razelle Kurzrock

Journal:

Clinical Breast Cancer

Year:

2010

Language:

english

File:

PDF, 132 KB

english, 2010

12

A phase I study of hepatic arterial infusion of nab-paclitaxel in combination with intravenous gemcitabine and bevacizumab for patients with advanced cancers and predominant liver metastases

Tsimberidou, Apostolia M., Ye, Yang, Wheler, Jennifer, Naing, Aung, Hong, David, Nwosu, Uchechi, Hess, Kenneth R., Wolff, Robert A.

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2013

Language:

english

File:

PDF, 270 KB

english, 2013

13

Bevacizumab-based treatment in colorectal cancer with aNRASQ61K mutation

Filip Janku, Jennifer J. Wheler, David S. Hong, Razelle Kurzrock

Journal:

Targeted Oncology

Year:

2013

Language:

english

File:

PDF, 344 KB

english, 2013

14

Phase I clinical trial of lenalidomide in combination with sorafenib in patients with advanced cancer

Prasanth Ganesan, Sarina Piha-Paul, Aung Naing, Gerald Falchook, Jennifer Wheler, Siqing Fu, David S. Hong, Razelle Kurzrock, Filip Janku, Shell Laday, Agop Y. Bedikian, Merrill Kies, Robert A. Wolff,

Journal:

Investigational New Drugs

Year:

2014

Language:

english

File:

PDF, 258 KB

english, 2014

15

A phase 1 study of gemcitabine combined with dasatinib in patients with advanced solid tumors

David S. Hong, Jennifer Hsing Choe, Aung Naing, Jennifer J. Wheler, Gerald S. Falchook, Sarina Piha-Paul, Stacy L. Moulder, Goldy C. George, Jonathan M. Choe, Lewis C. Strauss, Gary E. Gallick, Razell

Journal:

Investigational New Drugs

Year:

2013

Language:

english

File:

PDF, 335 KB

english, 2013

16

Phase I clinical trial of lenalidomide in combination with temsirolimus in patients with advanced cancer

Ganesan, Prasanth, Piha-Paul, Sarina, Naing, Aung, Falchook, Gerald, Wheler, Jennifer, Janku, Filip, Zinner, Ralph, Laday, Shell, Kies, Merrill, Tsimberidou, Apostolia M.

Journal:

Investigational New Drugs

Year:

2013

Language:

english

File:

PDF, 341 KB

english, 2013

17

Phase I study of anti-VEGF monoclonal antibody bevacizumab and histone deacetylase inhibitor valproic acid in patients with advanced cancers

Wheler, Jennifer J., Janku, Filip, Falchook, Gerald S., Jackson, Tiffiny L., Fu, Siqing, Naing, Aung, Tsimberidou, Apostalia M., Moulder, Stacy L., Hong, David S., Yang, Hui, Piha-Paul, Sarina A., Atk

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2014

Language:

english

File:

PDF, 386 KB

english, 2014

18

Phase I dose-escalating study of TAS-106 in combination with carboplatin in patients with solid tumors

Naing, Aung, Fu, Siqing, Zinner, Ralph G., Wheler, Jennifer J., Hong, David S., Arakawa, Kazuhito, Falchook, Gerald S., Kurzrock, Razelle

Journal:

Investigational New Drugs

Year:

2014

Language:

english

File:

PDF, 147 KB

english, 2014

19

MABp1, a first-in-class true human antibody targeting interleukin-1α in refractory cancers: an open-label, phase 1 dose-escalation and expansion study

Hong, David S, Hui, David, Bruera, Eduardo, Janku, Filip, Naing, Aung, Falchook, Gerald S, Piha-Paul, Sarina, Wheler, Jennifer J, Fu, Siqing, Tsimberidou, Apostolia M, Stecher, Michael, Mohanty, Prasa

Journal:

The Lancet Oncology

Year:

2014

Language:

english

File:

PDF, 330 KB

english, 2014

20

Outcomes in 144 Patients With Colorectal Cancer Treated in a Phase I Clinic: The MD Anderson Cancer Center Experience

Hong, David S., Patel, Jesal C., Wheler, Jennifer, Naing, Aung, Garrido-Laguna, Ignacio, Falchook, Gerald, Fu, Siqing, Tsimberidou, Apostolia M., Kopetz, Scott, Win, Sijin, Kurzrock, Razelle

Journal:

Clinical Colorectal Cancer

Year:

2012

Language:

english

File:

PDF, 472 KB

english, 2012

21

Exploratory study of carboplatin plus the copper-lowering agent trientine in patients with advanced malignancies

Fu, Siqing, Hou, Ming-Mo, Wheler, Jennifer, Hong, David, Naing, Aung, Tsimberidou, Apostolia, Janku, Filip, Zinner, Ralph, Piha-Paul, Sarina, Falchook, Gerald, Kuo, Macus Tien, Kurzrock, Razelle

Journal:

Investigational New Drugs

Year:

2014

Language:

english

File:

PDF, 480 KB

english, 2014

22

Evaluation of a novel blood pressure scoring method and its association with clinical response in cancer patients treated with anti-vascular endothelial growth factor therapy

Bilen, Mehmet Asim, Durand, Jean-Bernard, McQuinn, Lacey, Hess, Kenneth R., Fu, Siqing, Falchook, Gerald S., Hong, David S., Wheler, Jennifer J., Said, Rabih, Ewer, Michael S., Kurzrock, Razelle, Nain

Journal:

Investigational New Drugs

Year:

2014

Language:

english

File:

PDF, 187 KB

english, 2014

23

Methylation and histone deacetylase inhibition in combination with platinum treatment in patients with advanced malignancies

Falchook, Gerald S., Fu, Siqing, Naing, Aung, Hong, David S., Hu, Wei, Moulder, Stacy, Wheler, Jennifer J., Sood, Anil K., Bustinza-Linares, Ernesto, Parkhurst, Kristin L., Kurzrock, Razelle

Journal:

Investigational New Drugs

Year:

2013

Language:

english

File:

PDF, 274 KB

english, 2013

24

Dual inhibition of the vascular endothelial growth factor pathway: A phase 1 trial evaluating bevacizumab and AZD2171 (cediranib) in patients with advanced solid tumors

Hong, David S., Garrido-Laguna, Ignacio, Ekmekcioglu, Suhendan, Falchook, Gerald S., Naing, Aung, Wheler, Jennifer J., Fu, Siqing, Moulder, Stacy L., Piha-Paul, Sarina, Tsimberidou, Apostolia M., Wen,

Journal:

Year:

2014

Language:

english

File:

PDF, 349 KB

english, 2014

25

MET Abnormalities in Patients With Genitourinary Malignancies and Outcomes With c-MET Inhibitors

Jardim, Denis L.F., de Melo Gagliato, Débora, Falchook, Gerald, Zinner, Ralph, Wheler, Jennifer J., Janku, Filip, Subbiah, Vivek, Piha-Paul, Sarina A., Fu, Siqing, Tannir, Nizar, Corn, Paul, Tang, Cha

Journal:

Clinical Genitourinary Cancer

Year:

2015

Language:

english

File:

PDF, 506 KB

english, 2015

26

Analysis of MET Genetic Aberrations in Patients With Breast Cancer at MD Anderson Phase I Unit

de Melo Gagliato, Debora, Jardim, Denis L. Fontes, Falchook, Gerald, Tang, Chad, Zinner, Ralph, Wheler, Jennifer J., Janku, Filip, Subbiah, Vivek, Piha-Paul, Sarina A., Fu, Siqing, Hess, Kenneth, Roy-

Journal:

Clinical Breast Cancer

Year:

2014

Language:

english

File:

PDF, 234 KB

english, 2014

27

Dual antiangiogenic inhibition: a phase I dose escalation and expansion trial targeting VEGF-A and VEGFR in patients with advanced solid tumors

Falchook, Gerald S., Wheler, Jennifer J., Naing, Aung, Piha-Paul, Sarina A., Fu, Siqing, Tsimberidou, Apostolia M., Hong, David S., Janku, Filip, Zinner, Ralph, Jiang, Yunfang, Huang, Mei, Lin, Quan,

Journal:

Investigational New Drugs

Year:

2015

Language:

english

File:

PDF, 652 KB

english, 2015

28

Olanzapine for cachexia in patients with advanced cancer: an exploratory study of effects on weight and metabolic cytokines

Naing, Aung, Dalal, Shalini, Abdelrahim, Maen, Wheler, Jennifer, Hess, Kenneth, Fu, Siqing, Hong, David S., Janku, Filip, Falchook, Gerald S., Ilustre, Alyson, Ouyang, Fengying, Kurzrock, Razelle

Journal:

Supportive Care in Cancer

Year:

2015

Language:

english

File:

PDF, 345 KB

english, 2015

29

A phase I trial of combination trastuzumab, lapatinib, and bevacizumab in patients with advanced cancer

Falchook, Gerald S., Moulder, Stacy, Naing, Aung, Wheler, Jennifer J., Hong, David S., Piha-Paul, Sarina A., Tsimberidou, Apostolia M., Fu, Siqing, Zinner, Ralph, Janku, Filip, Jiang, Yunfang, Huang,

Journal:

Investigational New Drugs

Year:

2015

Language:

english

File:

PDF, 362 KB

english, 2015

30

Phase I trial of valproic acid and lenalidomide in patients with advanced cancer

Bilen, Mehmet Asim, Fu, Siqing, Falchook, Gerald S., Ng, Chaan S., Wheler, Jennifer J., Abdelrahim, Maen, Erguvan-Dogan, Basak, Hong, David S., Tsimberidou, Apostolia M., Kurzrock, Razelle, Naing, Aun

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2015

Language:

english

File:

PDF, 359 KB

english, 2015

31

Xilonix, a novel true human antibody targeting the inflammatory cytokine interleukin-1 alpha, in non-small cell lung cancer

Hong, David S., Janku, Filip, Naing, Aung, Falchook, Gerald S., Piha-Paul, Sarina, Wheler, Jennifer J., Fu, Siqing, Tsimberidou, Apostolia M., Stecher, Michael, Mohanty, Prasant, Simard, John, Kurzroc

Journal:

Investigational New Drugs

Year:

2015

Language:

english

File:

PDF, 713 KB

english, 2015

32

Next generation sequencing of exceptional responders with BRAF-mutant melanoma: implications for sensitivity and resistance

Wheler, Jennifer, Yelensky, Roman, Falchook, Gerald, Kim, Kevin B, Hwu, Patrick, Tsimberidou, Apostolia M, Stephens, Philip J, Hong, David, Cronin, Maureen T, Kurzrock, Razelle

Journal:

Year:

2015

Language:

english

File:

PDF, 995 KB

english, 2015

33

Phase I Clinical Trials in 56 Patients with Thyroid Cancer: The M. D. Anderson Cancer Center Experience

Tsimberidou, Apostolia Maria, Vaklavas, Christos, Wen, Sijin, Hong, David, Wheler, Jennifer, Ng, Chaan, Naing, Aung, Tse, Susan, Busaidy, Naifa, Markman, Maurie, Sherman, Steven I., Kurzrock, Razelle

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2009

Language:

english

File:

PDF, 163 KB

english, 2009

34

PCI-24781, a Novel Hydroxamic Acid HDAC Inhibitor, Exerts Cytotoxicity and Histone Alterations via Caspase-8 and FADD in Leukemia Cells

Rivera-Del Valle, Nilsa, Gao, Shan, Miller, Claudia P., Fulbright, Joy, Gonzales, Carolina, Sirisawad, Mint, Steggerda, Susanne, Wheler, Jennifer, Balasubramanian, Sriram, Chandra, Joya

Journal:

International Journal of Cell Biology

Year:

2010

Language:

english

File:

PDF, 831 KB

english, 2010

35

Inhibition of the Ras/Raf/MEK/ERK and RET Kinase Pathways with the Combination of the Multikinase Inhibitor Sorafenib and the Farnesyltransferase Inhibitor Tipifarnib in Medullary and Differentiated Thyroid Malignancies

Hong, David S., Cabanillas, Maria E., Wheler, Jennifer, Naing, Aung, Tsimberidou, Apostolia M., Ye, Lei, Waguespack, Steven G., Hernandez, Mike, El Naggar, Alder K., Bidyasar, Savita, Wright, John, Sh

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2011

Language:

english

File:

PDF, 564 KB

english, 2011

36

Multiple gene aberrations and breast cancer: lessons from super-responders

Wheler, Jennifer J., Atkins, Johnique T., Janku, Filip, Moulder, Stacy L., Yelensky, Roman, Stephens, Philip J., Kurzrock, Razelle

Journal:

Year:

2015

Language:

english

File:

PDF, 1.33 MB

english, 2015

37

Dose-finding study of hepatic arterial infusion of irinotecan-based treatment in patients with advanced cancers metastatic to the liver

Said, Rabih, Kurzrock, Razelle, Naing, Aung, Hong, David S., Fu, Siqing, Piha-Paul, Sarina A., Wheler, Jennifer J., Janku, Filip, Kee, Bryan K., Bidyasar, Savita, Lim, Joann, Wallace, Michael, Tsimber

Journal:

Investigational New Drugs

Year:

2015

Language:

english

File:

PDF, 330 KB

english, 2015

38

Novel Phase I Study Combining G1 Phase, S Phase, and G2/M Phase Cell Cycle Inhibitors in Patients with Advanced Malignancies

Jain, Rajul K., Hong, David S., Naing, Aung, Wheler, Jennifer, Helgason, Thorunn, Shi, Nai-Yi, Gad, Yash, Kurzrock, Razelle

Journal:

Year:

2015

Language:

english

File:

PDF, 1.36 MB

english, 2015

39

Phase 1 study of APTO-253 HCl, an inducer of KLF4, in patients with advanced or metastatic solid tumors

Cercek, Andrea, Wheler, Jennifer, Murray, Peter E., Zhou, Shawn, Saltz, Leonard

Journal:

Investigational New Drugs

Year:

2015

Language:

english

File:

PDF, 270 KB

english, 2015

40

Phase I clinical trial of lenalidomide in combination with 5-fluorouracil, leucovorin, and oxaliplatin in patients with advanced cancer

Said, Rabih, Ye, Yang, Hong, David S., Naing, Aung, Falchook, Gerald, Fu, Siqing, Wheler, Jennifer J., Piha-Paul, Sarina, Tsimberidou, Apostolia-Maria

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 604 KB

english, 2016

41

Phase I clinical trial of lenalidomide in combination with bevacizumab in patients with advanced cancer

Said, Rabih, Kakadiaris, Eugenia, Piha-Paul, Sarina, Fu, Siqing, Falchook, Gerald, Janku, Filip, Wheler, Jennifer J., Zinner, Ralph, Hong, David S., Kurzrock, Razelle, Tsimberidou, Apostolia M.

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 430 KB

english, 2016

42

Characteristics and outcomes for patients with advanced vaginal or vulvar cancer referred to a phase I clinical trials program: the MD Anderson cancer center experience

Fu, Siqing, Shi, Naiyi, Wheler, Jennifer, Naing, Aung, Janku, Filip, Piha-Paul, Sarina, Gong, Jing, Hong, David, Tsimberidou, Apostolia, Zinner, Ralph, Subbiah, Vivek, Hou, Ming-Mo, Ramirez, Pedro, Ra

Journal:

Gynecologic Oncology Research and Practice

Year:

2015

Language:

english

File:

PDF, 749 KB

english, 2015

43

Benchmarking the Oil and Gas Industry

Miessler, Ray, Pappas, James, Wheler, Jennifer

Journal:

Year:

2012

Language:

english

File:

PDF, 647 KB

english, 2012

44

Association between new-onset hypothyroidism and clinical response in patients treated with tyrosine kinase inhibitor therapy in phase I clinical trials

Bilen, Mehmet Asim, Patel, Amy, Hess, Kenneth R., Munoz, Javier, Busaidy, Naifa L., Wheler, Jennifer J., Janku, Filip, Falchook, Gerald S., Hong, David S., Meric-Bernstam, Funda, Habra, Mouhammed Amir

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 418 KB

english, 2016

45

Outcomes of patients ≥65 years old with advanced cancer treated on phase I trials at MD Anderson Cancer Center

Subbiah, Ishwaria M., Wheler, Jennifer J., Hess, Kenneth R., Hong, David S., Naing, Aung, Fu, Siqing, Kurzrock, Razelle, Tsimberidou, Apostolia M.

Journal:

International Journal of Cancer

Year:

2016

Language:

english

File:

PDF, 769 KB

english, 2016

46

Phase I Dose‐Escalation Study of Pilaralisib (SAR245408, XL147) in Combination with Paclitaxel and Carboplatin in Patients with Solid Tumors

Wheler, Jennifer, Mutch, David, Lager, Joanne, Castell, Christelle, Liu, Li, Jiang, Jason, Traynor, Anne M.

Journal:

Year:

2017

Language:

english

File:

PDF, 506 KB

english, 2017

47

A phase 2 randomised discontinuation trial of cabozantinib in patients with ovarian carcinoma

Vergote, Ignace B., Smith, David C., Berger, Raanan, Kurzrock, Razelle, Vogelzang, Nicholas J., Sella, Avishay, Wheler, Jennifer, Lee, Yihua, Foster, Paul G., Weitzman, Ron, Buckanovich, Ronald J.

Journal:

European Journal of Cancer

Year:

2017

Language:

english

File:

PDF, 543 KB

english, 2017

48

Phase I study of the combination of crizotinib (as a MET inhibitor) and dasatinib (as a c-SRC inhibitor) in patients with advanced cancer

Kato, Shumei, Jardim, Denis L., Johnson, Faye M., Subbiah, Vivek, Piha-Paul, Sarina, Tsimberidou, Apostolia M., Falchook, Gerald S., Karp, Daniel, Zinner, Ralph, Wheler, Jennifer, Janku, Filip, Fu, Si

Journal:

Investigational New Drugs

Year:

2017

Language:

english

File:

PDF, 827 KB

english, 2017

49

Outcomes of patients with sarcoma enrolled in clinical trials of pazopanib combined with histone deacetylase, mTOR, Her2, or MEK inhibitors

Dembla, Vikas, Groisberg, Roman, Hess, Ken, Fu, Siqing, Wheler, Jennifer, Hong, David S., Janku, Filip, Zinner, Ralph, Piha-Paul, Sarina Anne, Ravi, Vinod, Benjamin, Robert S., Patel, Shreyaskumar, So

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 1.33 MB

english, 2017

50

Phase I Clinical Trial of Bendamustine and Bevacizumab for Patients With Advanced Cancer

Tsimberidou, Apostolia M., Adamopoulos, Alexandra M., Ye, Yang, Piha-Paul, Sarina, Janku, Filip, Fu, Siqing, Hong, David, Falchook, Gerald S., Naing, Aung, Wheler, Jennifer, Fortier, Adoneca, Kurzrock

Journal:

Journal of the National Comprehensive Cancer Network

Year:

2014

Language:

english

File:

PDF, 435 KB

english, 2014

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